Emerging roles of long non-coding RNAs in keloids

Emerging roles of long non-coding RNAs in keloids

Blog Article

Keloids are pathologic wound healing conditions caused by fibroblast hyperproliferation and may pride peach tree excess collagen deposition following skin injury or irritation, which significantly impact patients by causing psychosocial and functional distress.Extracellular matrix (ECM) deposition and human fibroblast proliferation represents the main pathophysiology of keloid.Long non-coding RNAs (LncRNAs) play important roles in many biological and pathological processes, including development, differentiation and carcinogenesis.

Recently, accumulating evidences have demonstrated that deregulated lncRNAs contribute to keloids formation.The present review summarizes the researches of deregulated lncRNAs in keloid.Exploring lncRNA-based methods exhaust tips for chrysler 300 hold promise as new effective therapies against keloid.